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Company Brand Name Salt Combination Main Medical Class Sub Medical Class From Zydus Cadila :: MENODAC Menotrophin #N/A #N/A. Indications for Drugs :: Infertility, Assisted reproductive technologies, Polycystic ovarian disease, In vitro fertilisation procedures. Unless prescribed otherwise, doses are as follows: Sterility in Females: The dosage of HMG for the induction of follicle growth in normo- or hypogonadotrophic women varies according to the individual. The amount depends on ovarian reaction and should be checked by ultrasound examinations of the ovaries and measuring estradiol levels. If the HMG dosage is too high for the treated individual, multiple uni- and bilateral follicle growth can occur. HMG is administered IM or SC and in general, the therapy is begun with a daily dosage corresponding to 75-150 IU FSH + 75-150 IU LH daily. If the ovaries do not respond, the dosage can slowly be increased until a rise in estradiol secretion and follicle growth is evident. Treatment with the same dosage of HMG continues until the preovulatory estradiol serum level is attained. If the level rises too quickly, the dosage should be reduced. To induce ovulation, hCG 5000 or 10,000 IU are injected IM 1-2 days after the last HMG administration. Note: After administering a HMG dosage which is too high for the corresponding individual, a subsequent hCG administration can cause an unintentional hyperstimulation of the ovaries. Sterility in Males: Initially, 3 x 1000 and 3000 IU hCG a week are administered until a normal testosterone serum level is reached. Then, an additional dose of HMG 3 x (75-150 IU FSH + 75-150 IU LH)/week is administered IM for a few months. Females: Pregnancy, enlargement of the ovaries or cysts that is not caused by polycystic ovarian syndrome, gynaecological bleeding of unknown cause and tumors in the uterus, ovaries and breasts. Males: Carcinoma of the prostate and tumors in the testes, stanozolol 50 mg inyectable. The following conditions must be properly treated before therapy with HMG is begun: Dysfunctions of the thyroid gland and of the cortex of the suprarenal gland, a rise in the serum level of prolactin with different causes (hyperprolactinaemia), tumors in the pituitary gland (hypophysis) or in part of the diencephalon (hypothalamus). When treating sterile women, ovarian activity should be checked (ultrasound and estradiol levels in serum response) prior to HMG administration. During treatment, these tests should be carried out every 1-2 days until stimulation occurs. Ovarian reaction can also be measured using a cervix index. Close supervision is imperative during treatment. Treatment should be immediately discontinued if unintentional hyperstimulation occurs. Further remarks concerning the steps to be taken when ovarian hyperstimulation has occurred can be found under Actions. Drug Side Effects :: Occasionally, nausea and vomiting can occur. In single cases, hypersensitivity reactions and fever can occur during treatment with HMG. The administration of Menogon may lead to reactions at the injection site: Reddening, pain, swelling and itching.
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