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Appearance of, or increasing acne and other skin rashes or ailments Male pattern baldness Edema (water retention/swelling) Striae (stretch marks) Immune System. Hep B or Hep C, HIV infection (if needles are shared) Psychological. Mood swings Aggressive, even violent behavior Depression Psychotic episodes Addiction. Because anabolic steroids are derived from testosterone, they can have profound effects on the hormone levels of both male and female abusers. These effects can cause any or all of the following problems in men: Temporary infertility or sterility (reversible) Altered sex drive Prostate enlargement, and increased prostate cancer risk Irreversible breast enlargement Painful erections Shrinkage of the testicles Reduced levels of testosterone Abnormal sperm production Increased levels of estrogen. 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