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Mechanism of action: breast cancer cell growth is often estrogen-dependent and anti-tumour activity is expected following effective and continuous estrogen. — many breast cancer tumors grow in response to estrogen. Exemestane interferes with the production of estrogen in the body. Tion of chemotherapy in patients unselected for estrogen receptor. Aromasin(exemestane): exemestane is indicated for the adjuvant treatment of post-menopausal women with estrogen receptor positive early breast cancer who h. Exemestane is an anti-cancer hormone therapy. It is classified as an "aromatase inhibitor. " (for more detail see "how exemestane works" below). Aromasin is the brand name for a drug known as exemestane and it too is an anti-estrogen drug. Primarily, however, the main difference between these drugs. 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