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Although 1 out of 3 people who uses androgenic-anabolic steroids develops a steroid use disorder, the effects of the drugs on the central nervous system and the psyche are still not well understood.[i]

The main effects of steroids are:

They can increase the levels of testosterone in the body, especially in men. They can make men feel stronger and more aggressive.

The use of androgens affects the brain as well as the cardiovascular system.[1]

Treatment Guidelines

Treatment of Androgenic Anabolic Steroid Syndrome (AAS) is done through the use of a testosterone and estrogen supplementation.

The main dosage of testosterone is at least 2.3 percent on average.

The use of estrogen is not recommended for male patients because they will not benefit from the benefits of testosterone supplementation.[1]

Some studies suggest that patients will respond better on the treatment of female patients with AAS.[1]

In a study done in 2008, a group of young athletes found significant improvement in sexual function with androgen administration over a six month period.[ii]

The study concluded that: «androstenedione treatment significantly improved sexual function in adolescent male athletes after the completion of 6 months of treatment.»

A new, double blind, randomized trial in female AAS users, administered at the end of the study in two groups of female football players, had only one male participant. Although this was an isolated trial, its results suggest that when it comes to sexual function, testosterone and estrogen supplementation may be more beneficial with these patients.[i]

A controlled study performed in China in 2012 found that testosterone-based therapy may be effective in women with mild androgenic alopecia using testosterone (tamoxifen) for 3 years. The study suggests that testosterone can be used with a low dose and be effective with short-term therapy.[iii]

The researchers discovered some important differences between women, including women receiving androgen-based therapy and those receiving placebo or a placebo substitute. During the study, the researchers found that for women receiving estrogen, the therapy had no advantage over placebo, whereas there was a good result for men receiving the same combination of oral testosterone, estrogen therapy and placebo.

A placebo-controlled study in a different country published in 2013 also suggests that the testosterone treatment might be effective in treating mild androgenic alopecia.[iv]

Conclusion

We do not know yet if androgenic-anabolic steroid use disorders are more prevalent in men than in women. The most frequent use of androgenic-anabolic steroids is in young adult males. There’s some evidence that

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